Understanding TIVICAY® (dolutegravir)

FAQs About TIVICAY

Learning as much as you can about treatment choices can help make conversations with your healthcare provider even more productive. Below you will find some of the most common questions about HIV-1 treatment and TIVICAY.

WHAT IS TIVICAY?

TIVICAY is a prescription medicine that is used to treat Human Immunodeficiency Virus‑1 (HIV‑1) infection together with:

  • other antiretroviral medicines in adults and children who weigh at least 66 pounds (30 kg).
  • rilpivirine in adults to replace their current anti‑HIV‑1 medicines when their healthcare provider determines that they meet certain requirements.

HIV‑1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS).

It is not known if TIVICAY is safe and effective in children who weigh less than 66 pounds (30 kg) or in children who have received certain types of medicine for HIV‑1 infection.

HOW SHOULD I TAKE TIVICAY?

  • Take TIVICAY exactly as your healthcare provider tells you to take it.
  • Take TIVICAY with or without food.
  • Do not change your dose or stop taking TIVICAY without talking with your healthcare provider.
  • If you take antacids, laxatives, or other medicines that contain aluminum, magnesium, or buffered medicines, TIVICAY should be taken at least 2 hours before or 6 hours after you take these medicines.
  • If you need to take iron or calcium supplements by mouth during treatment with TIVICAY:
    • If you take TIVICAY with food, you may take these supplements at the same time that you take TIVICAY.
    • If you do not take TIVICAY with food, take TIVICAY at least 2 hours before or 6 hours after you take these supplements.
  • Do not miss a dose of TIVICAY.
  • If you miss a dose of TIVICAY, take it as soon as you remember. Do not take 2 doses at the same time or take more than your prescribed dose.
  • Stay under the care of a healthcare provider during treatment with TIVICAY.
  • Do not run out of TIVICAY. The virus in your blood may increase and the virus may become harder to treat. When your supply starts to run low, get more from your healthcare provider or pharmacy.
  • If you take too much TIVICAY, call your healthcare provider or go to the nearest hospital emergency room right away.

WHAT ARE THE POSSIBLE SIDE
EFFECTS OF TIVICAY?

HOW SHOULD I STORE TIVICAY?

  • Store TIVICAY at room temperature between 68°F to 77°F (20°C to 25°C).
  • Store TIVICAY 10‑mg tablets in the original bottle. Keep the bottle tightly closed and protected from moisture.
  • The bottle of TIVICAY (10‑mg tablets) contains a desiccant packet to help keep your medicine dry (protect it from moisture). Do not remove the desiccant packet from the bottle.

Keep TIVICAY and all medicines out of the reach of children.

GENERAL INFORMATION ABOUT THE SAFE AND EFFECTIVE
USE OF TIVICAY.

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use TIVICAY for a condition for which it was not prescribed. Do not give TIVICAY to other people, even if they have the same symptoms you have. It may harm them. You can ask your healthcare provider or pharmacist for information about TIVICAY that is written for health professionals. For more information, go to www.TIVICAY.com or call 1-877-844-8872.

WHAT ARE THE INGREDIENTS IN TIVICAY?

Active ingredient: dolutegravir.

Inactive ingredients: D‑mannitol, microcrystalline cellulose, povidone K29/32, sodium starch glycolate, and sodium stearyl fumarate. The tablet film‑coating contains the inactive ingredients iron oxide yellow (for the 25‑mg and 50‑mg tablets only), macrogol/PEG, polyvinyl alcohol‑part hydrolyzed, talc, and titanium dioxide.