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Tips for Taking Your HIV-1 Medicines

Why sticking to your treatment
plan matters.

You and your healthcare provider will decide which
HIV-1 medicines you should take. Youneed to know exactly how much of each HIV-1 medicine to take, as well as when and howto take it. The goal is to keep the right amount of each medicine in your body at all times. This can help your viral load stay low and your CD4 cell count stay high. Skippingdoses gives the virus a chance to get worse or even change form.
When that happens,your medicines might not be
able to control the new form of HIV.

HIV-1 medicine reminders

There are many reasons why people may not take their HIV-1 medicines as directed, but oneof the most
common is just plain forgetfulness. Luckily, there are
simple steps you cantake to help avoid this problem.
These tips can help you remember to take your
medicinesand stay on track with your HIV-1 treatment plan:

  • Set a watch or cell phone alarm to go off
    when it is time to take yourHIV-1 medicines.
  • Buy a pillbox. Use it to organize your HIV-1
    medicines once a week/month and stayon
    track every day.
  • Try to make taking your medicines part of
    your daily routine.
    It helps if youtake your
    HIV-1 medicines at the same time you do
    something else, such as eating ameal or
    getting ready for bed.
  • You may want to create a daily or weekly
    medicine schedule
    . It couldhelp to include
    pictures of your medicines so you know
    exactly what you’resupposed to take. You
    can do this on the computer or by hand. Just
    be sureto make copies.
  • Never hesitate to call your healthcare
    provider or pharmacist
    if you are running
    low on your HIV medicine. Always make sure
    you have enough of what you need!

No matter what method you use, it’s very important
that you take all of your medicines
exactly as your
healthcare provider has prescribed. Living with HIV means not letting it take control of your life. Staying on track with your HIV-1 treatment plan is the
first step.

What is TIVICAY?

TIVICAY is a prescription medicine that is used to treat Human Immunodeficiency Virus‑1 (HIV‑1) infection together with:

  • other antiretroviral medicines in adults and children who weigh at least 66 pounds.
  • rilpivirine in adults to replace their current anti-HIV-1 medicines when their healthcare provider determines that they meet certain requirements.

HIV‑1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). It is not known if TIVICAY is safe and effective in children who weigh less than 66 pounds or in children who have received certain types of medicine for HIV-1 infection.


Who should not take TIVICAY?

  • Do not take TIVICAY if you:
    • have ever had an allergic reaction to a medicine that contains dolutegravir
    • take dofetilide

What are the possible side effects of TIVICAY?
TIVICAY can cause serious side effects, including:

  • Allergic reactions. Call your healthcare provider right away if you develop a rash with TIVICAY. Stop taking TIVICAY and get medical help right away if you develop a rash with any of the following signs or symptoms:
    • fever
    • general ill feeling
    • tiredness
    • muscle or joint aches
    • blisters or sores in mouth
    • blisters or peeling of the skin
    • redness or swelling of the eyes
    • swelling of the mouth, face, lips, or tongue
    • problems breathing
  • Liver problems. People with a history of hepatitis B or C virus may have an increased risk of developing new or worsening changes in certain liver tests during treatment with TIVICAY. Liver problems, including liver failure, have also happened in people without a history of liver disease or other risk factors. Your healthcare provider may do blood tests to check your liver. Call your healthcare provider right away if you develop any of the following signs or symptoms of liver problems:
    • your skin or the white part of your eyes turn yellow
    • dark or "tea-colored" urine
    • light-colored stools (bowel movements)
    • nausea or vomiting
    • loss of appetite
    • pain, aching, or tenderness on the right side of your stomach area
  • Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV-1 medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body. Tell your healthcare provider right away if you start having new symptoms after you start taking TIVICAY.
  • The most common side effects of TIVICAY include: trouble sleeping, tiredness, and headache.

These are not all the possible side effects of TIVICAY. Call your doctor for medical advice about side effects.

What should I tell my healthcare provider before taking TIVICAY?

Before you take TIVICAY, tell your healthcare provider about all of your medical conditions, including if you:

  • have ever had an allergic reaction to dolutegravir.
  • have had liver problems, including hepatitis B or C.
  • are pregnant or plan to become pregnant. TIVICAY may harm your unborn baby.
    • You should not take TIVICAY at the time of becoming pregnant or during the first 12 weeks of pregnancy. Your healthcare provider may change your medicine during this time in your pregnancy
    • If you can become pregnant, your healthcare provider will perform a pregnancy test before you start treatment with TIVICAY, and you should consistently use effective birth control (contraception) during treatment with TIVICAY
    • Tell your healthcare provider right away if you are planning to become pregnant, you become pregnant, or think you may be pregnant during treatment with TIVICAY
  • are breastfeeding or plan to breastfeed. Do not breastfeed if you take TIVICAY. It is not known if TIVICAY can pass to your baby in your breast milk. Talk with your healthcare provider about the best way to feed your baby.
  • Tell your healthcare provider about the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines interact with TIVICAY. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine. You can ask your healthcare provider or pharmacist for a list of medicines that interact with TIVICAY. Do not start taking a new medicine without telling your healthcare provider. Your healthcare provider can tell you if it is safe to take TIVICAY with other medicines.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.

Please read the Patient Information for TIVICAY and discuss it with your healthcare provider.

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